Treatment for COVID-19

Treatment for COVID-19

See a video describing treatment options in العربية (Arabic) | မြန်မာစာ (Burmese) | Dari / دری | Français (French)| Kirundi | Maay Maay | नेपाली (Nepali) | Pashto /پښتو | Soomaali | Español (Spanish) | Swahili | Tiếng Việt (Vietnamese) | American Sign Language

Who should GEt COVID-19 Treatment?

Some people are more likely to get very sick from COVID-19. If you are age 65 or older or have a medical condition that may put you at risk, reach out to your health care provider to ask about treatment — as soon as you get a positive test result.

Find out if you are at risk

Do not delay in seeking treatment even if:

  • You are vaccinated. Vaccination protects against serious illness, but some people also need treatment to keep them out of the hospital. 
  • Your symptoms are mild. Symptoms can change and you could get much sicker quickly.

By getting treatment, you could have less serious symptoms and may lower the chances of your illness getting worse and needing care in the hospital.

Learn more about COVID-19 treatments and medications from the CDC

ANtiviral treatments

PaxlovidTM or LAGEVRIOTM (molnupiravir) are antivirals, targeting specific parts of the virus to stop it from multiplying in the body, helping to prevent severe illness and death. Both medications are taken by mouth. They should be started as soon as possible and must begin within 5 days of when your symptoms start. Paxlovid is 87% effective in preventing hospitalizations/deaths and is widely available in Vermont.

Learn more about oral antiviral treatments

If you do not have a health care provider, call 2-1-1 to be connected to care, or contact the nearest federally qualified health center or one of Vermont's free & referral clinics.

The CDC has advised about the potential for mild COVID-19 symptoms to return briefly, also called “rebound.” This can happen whether you have taken Paxlovid or not. If you are at risk for serious illness from COVID-19, it is still important to take Paxlovid when prescribed by your health care provider to protect yourself. If symptoms do return, stay isolated until you are well to prevent further transmission. You do not need to take Paxlovid again.


Your body naturally makes antibodies to fight infection. However, your body may not have sufficient antibodies to recognize a new virus like the one that causes COVID-19. Monoclonal antibodies such as bebtelovimab are made in a laboratory and are given to patients directly with an infusion into a vein (intravenously, or through an IV).  

The antibodies attach to the virus that causes COVID-19, which then blocks the virus from entering cells of the body. So treatment with monoclonal antibodies may slow the infection. They provide temporary, enhanced immunity, which can help keep a person with COVID-19 from progressing to more severe symptoms.

Your health care provider can refer you to an infusion center where COVID-19 therapeutics can be given. There is no cost to anyone for the COVID-19 therapeutics themselves, but there may be treatment fees. If you do not have insurance, ask the facility if there will be a charge.

Learn more about monoclonal antibodies


For people who are immunocompromised or who are unable to receive the vaccine, there is a long-acting monoclonal treatment available that has received Emergency Use Authorization called Evusheld. This drug is administered through an injection and has shown a 77% reduction in developing COVID-19 symptoms. Talk to your provider to see if this product is an option for you.